Selected Publications -

1. Xian-Jia Li, Meng-Cheng Zhang, Xiang Li, Lu−Lu Guan, Yu-Ru Liang*, Er-Jun Hao*, Yang Wang*, Hai-Ming Guo*, Discovery of Novel Oxazolo[4,3-f]purine Derivatives as Antitumor Agents through PPIA Interaction, J. Med. Chem., 2025, Articles ASAP (Article).

2. Qi-Liang Yang*, Rong-Yi Xu, Cheng-Yang Ni, Xin Liu, Zu-Lin Qiao, Qi-Ying Zhang, Dong-Chao Wang, Hai-Ming Guo*, Electrochemical regioselective synthesis of sulfonyl 2,5-dihydrofuran-fused spiropyrimidines via multi-component radical cascade reactions, Green Chem., 2025, 27, 1499-1509.

Graphical abstract:Electrochemical regioselective synthesis of sulfonyl 2,5-dihydrofuran-fused spiropyrimidines via multi-component radical cascade reactions

3. Ying Hu, Heng-Bin Yu, Yin Tian*, Ming-Sheng Xie*, Hai-Ming Guo*, Copper(II)-Catalyzed Asymmetric (3+3) Annulation of Diaziridines with Oxiranes, Org. Lett., 2025, 27, 1310-1315. (Letter)

4. Wei-Jing Yang, Jun-Hao Zhang, Ning Li, Ming-Sheng Xie*, Hai-Ming Guo*, Ni(ii)-catalyzed enantioselective α-hydrazination of α-fluoroesters: access to chiral quaternary α-fluorinated α-amino acid derivatives, Org. Chem. Front., 2025, Advance Article.

5. Ning Li, Jun-Hao Zhang, Wei-Jing Yang, Ming-Sheng Xie*, Hai-Ming Guo*, Cu(II)-catalyzed asymmetric Mukaiyama–Michael reaction: concise synthesis of cyclohexadiene analogues, Org. Chem. Front., 2025, Advance Article.

Graphical abstract:Cu(ii)-catalyzed asymmetric Mukaiyama–Michael reaction:concise synthesis of cyclohexadiene analogues

2024 publications.

1. Tao Wei, Han-Le Wang, Yin Tian*, Ming-Sheng Xie*, Hai-Ming Guo*, Enantioselective construction of stereogenic-at-sulfur(IV) centres via catalytic acyl transfer sulfinylation, Nature Chemistry , 2024, 16, 1301-1311.

2. Heng-Bin Yu, Yang-Guang Chen, Yin Tian*, Ming-Sheng Xie*, Hai-Ming Guo*, Nickel(II)-Catalyzed Asymmetric Inverse-Electron-Demand Diels–Alder Reaction of 2-Pyrones with Styrenes and Indenes, ACS Catalysis, 2024, 14, 11, 8930-8938.

3. Er-Jun Hao*, Yan Zhao, Min Yu, Xian-Jia Li, Ke-Xin Wang, Fu-Ying Su, Yu-Ru Liang*, Yang Wang*, Hai-Ming Guo*, Discovery, Synthesis, and Activity Evaluation of Novel Five-Membered Sulfur-Containing Heterocyclic Nucleosides as Potential Anticancer Agents In Vitro and In Vivo, J. Med. Chem., 2024, 67, 15, 12553-12570.

4. Chen-Ying Hou, Chun Yang, Yin Tian*, Ming-Sheng Xie*, Hai-Ming Guo*, Achiral Counteranion-Induced Reversal of Enantioselectivity in Ni(II)-Catalyzed Friedel–Crafts Alkylation/Annulation of 2-Naphthols, Org. Lett., 2024, 26, 30, 6390-6395.

5. Tao Wei, Ming-Sheng Xie *, Hai-Ming Guo*, Construction of thioglycoside bonds via an asymmetric organocatalyzed sulfa-Michael/aldol reaction: access to 4′-thionucleosides, Chem. Commun., 2024, 60, 5018-5021. （Chemical Communications HOT Articles 2024）

Graphical abstract:Construction of thioglycoside bonds via an asymmetric organocatalyzed sulfa-Michael/aldol reaction:access to 4′-thionucleosides

6. Meng-Ru Li, Meng-Yao Zheng, Dong-Chao Wang*, Hai-Ming Guo*, Pd-catalyzed 5-exo-dig cyclization/etherification cascade of N-propargyl arylamines for the synthesis of polysubstituted furans, Chem. Commun., 2024, 60, 7721-7724.

Graphical abstract:Pd-catalyzed 5-exo-dig cyclization/etherification cascade of N-propargyl arylamines for the synthesis of polysubstituted furans

7. Ru-Lin Luo, Xiao-Bing Wang, Ming-Sheng Xie*, Hai-Ming Guo *, Catalytic asymmetric ring-opening of aminocyclopropanes with oxygen nucleophiles: access to chiral γ-amino acid derivatives , Org. Chem. Front., 2024, 11, 1817-1823.

Graphical abstract:Catalytic asymmetric ring-opening of aminocyclopropanes with oxygen nucleophiles:access to chiral γ-amino acid derivatives

8. Jun-Hao Zhang, Wei-Jing Yang, Ning Li, Yin Tian*, Ming-Sheng Xie*, Hai-Ming Guo*, Reversal of enantioselectivity in cobalt(II)-catalyzed asymmetric Michael–alkylation reactions: synthesis of spiro-cyclopropane-oxindoles, Org. Chem. Front., 2024, 11, 4007-4013.

Graphical abstract:Reversal of enantioselectivity in cobalt(ii)-catalyzed asymmetric Michael–alkylation reactions:synthesis of spiro-cyclopropane-oxindoles

9. Han-Le Wang, Tao Wei, Ru-Yun Bi, Ming-Sheng Xie*, Hai-Ming Guo*, Imidazolidine-Pyrroloimidazolone Pyridine-Ni(acac)₂ Complex Catalyzed Asymmetric Darzens Reaction of Isatins with Phenacyl Chlorides: A Chiral Amplification Effect, Adv. Synth. Catal., 2024, 3188-3193.

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10. Ting-Ting Yang, Yun-Qiao Zhang, Ming-Sheng Xie, Yin Tian*, Dong-Chao Wang*, Hai-Ming Guo*, Dearomative [2 + 1] Spiroannulation of Bromophenols with Electron-Deficient Alkenes, J. Org. Chem., 2024, 89, 11, 8041-8054.

11. Hai-Ting Wang, Xiao-Lin Wen, Xiao-Lin Xu, Dong-Chao Wang*, Hai-Ming Guo*, A domino [3 + 2] cycloaddition/deamination/imine hydrolysis reaction of cyclopropyl spirooxindoles with thiourea for access to spiro-γ-thiolactone oxindoles, Org. Chem. Front., 2024, 11, 4416-4422.

12. Qi-Liang Yang*, Na-Na Guo, Shu-Xian Liu, Bei-Ning Zhang, Guodong Zou, Hai-Xia Wang, Dong-Chao Wang, Hai-Ming Guo*, Electrooxidative iridium-catalyzed sp² C–H activation–annulation leading to cationic π-extended heteroaromatics, Org. Chem. Front., 2024, 11, 4849-4856.

13. Qian Zhang*, Tian-Jiao Yue, Shi-Jie Jiang, Hai-Ming Guo*, Linking Nitrogen-Rich Pillar[5]arene to Hyper-Cross-Linked Polymers for Efficient and Simultaneous Capture of Iodine and Methyl Iodide, ACS Applied Polymer Materials, 2024, 4, 5507-5515.

14. Yu-Lin Gao, Yang Yang, Chen Wu, Ming-Sheng Xie*, Hai-Ming Guo*, Chemoselectivity Switch between Enantioselective [2,3]-Wittig Rearrangement and Conia-Ene-Type Reactions of Propargyloxyoxindoles, Chem. Eur. J. 2024, e202402556. (Dedicated to Professor Xiaoming Feng and Professor Yong Tang on the occasion of their 60th Birthdays.)

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