详细介绍



姓名:袁梦,性别:女,学历:博士,职称:讲师,职位:无

荣誉

联系方式:mg1735014@smail.nju.edu.cn


教育经历:

20139-20176月 山东师范大学生命科学学院 获学士学位

20179-20246月 南京大学医学院,硕博连读 获博士学位


工作经历:

20251月至今 抗病毒性传染病创新药物全国重点实验室  讲师


研究领域与兴趣:

主要从事抗病毒性药物筛选以及病毒感染致病分子机制研究;病原体通过细胞外小囊泡(Extracellular Vesicles,EVs)跨物种传播以及致病机制研究与应用研究。

近年来主持的主要科研项目:


获奖:


代表性论文:

1. Yuan, M., X. Tian, et al. miRNA-431-5p enriched in EVs derived from IFN-beta stimulated MSCs potently inhibited ZIKV through CD95 downregulation. Stem Cell Res Ther, 2024 15(1): 435.

2. Yuan, M., W. Ma, et al. Delivery of therapeutic RNA by extracellular vesicles derived from Saccharomyces cerevisiae for medicine applications. J Pharm Sci 2024 113(12): 3574-3585.

3. Liu, B., X. Tian, L. Li, R. Zhang, J. Wu, N. Jiang, M. Yuan, D. Chen, A. Su, S. Xu and Z. Wu. Severe fever with thrombocytopenia syndrome virus induces lactylation of m6A reader protein YTHDF1 to facilitate viral replication. EMBO Rep 2024 25(12): 5599-5619.

4. Zou, X., M. Yuan, T. Zhang, N. Zheng and Z. Wu. EVs Containing Host Restriction Factor IFITM3 Inhibited ZIKV Infection of Fetuses in Pregnant Mice through Trans-placenta Delivery. Mol Ther 2021 29(1): 176-190.

5. Zhang, R., M. Cheng, B. Liu, M. Yuan, D. Chen, Y. Wang and Z. Wu. DEAD-Box Helicase DDX6 Facilitated RIG-I-Mediated Type-I Interferon Response to EV71 Infection. Front Cell Infect Microbiol 2021 11: 725392.

6. Zou, X., M. Yuan, T. Zhang, H. Wei, S. Xu, N. Jiang, N. Zheng and Z. Wu. Extracellular vesicles expressing a single-chain variable fragment of an HIV-1 specific antibody selectively target Env(+) tissues. Theranostics 2019 9(19): 5657-5671.







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